Over the past years, the chem(o)informatics field has further evolved and new application areas have opened up, for example, in the broadly defined area of chemical biology. Meer
Over the past 40 years the field of molecular simulations has evolved from picosecond studies of isolated macromolecules in vacuum to studies of complex, chemically heterogeneous biological systems consisting of millions of atoms, with the simulation time scales spanning up to milliseconds. Meer
"A stereotype of computer science textbooks is that they are dry, boring, and sometimes even intimidating. As a result, they turn students’ interests off from the subject matter instead of enticing them into it. Meer
This volume aims to provide a new perspective on the broader usage of Hidden Markov Models (HMMs) in biology. Hidden Markov Models: Methods and Protocols guides readers through chapters on biological systems; ranging from single biomolecule, cellular level, and to organism level and the use of HMMs in unravelling the complex mechanisms that govern these complex systems. Meer
The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes. Meer
In 1988, the NATO panel governing human sciences (Panel 8 on Defence Applica of Human and Bio-Medical Sciences) established a Research Study Group to synthe tions size information relevant to Advanced Technologies Applied to Training Design. Meer
This volume contains the edited texts of the lectures presented at the workshop on Nonlinear Optimization: Theory and Applications, held in Erice at the "G. Meer
Model-Based Systems Engineering (MBSE), which tackles architecting and design of complex systems through the use of formal models, is emerging as the most critical component of systems engineering. Meer
Gluecklich, die wissen, dass hinter allen Sprachen das Unsaegliche steht. Those are happy who know that behind all languages there is something unsaid Rainer Maria Rilke This book shows in a new way that a solution to a fundamental problem from one scienti? Meer
This thorough book provides a collection of techniques used in the emerging field of computational chemogenomics, which is an integration of chemoinformatics, bioinformatics, computer science, statistics, automated pattern recognition and modeling, database usage with data retrieval, and systems integration. Meer
Computer Organization: Basic Processor Structure is a class-tested textbook, based on the author’s decades of teaching the topic to undergraduate and beginning graduate students. Meer
Data Mining and Multi agent Integration aims to re?ect state of the art research and development of agent mining interaction and integration (for short, agent min ing). Meer
Complexity and dynamic order of controlled engineering systems is constantly increasing. Complex large scale systems (where "large" reflects the system’s order and not necessarily its physical size) appear in many engineering fields, such as micro-electromechanics, manufacturing, aerospace, civil engineering and power engineering. Meer
How can one trust computation taking place at a remote site, particularly if a party at that site might have motivation to subvert this trust? In recent years, industrial efforts have advanced the notion of a "trusted computing platform" as a building block. Meer
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