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The pharmaceutical industry is under increasing pressure to do more with less. Drug discovery, development, and clinical trial costs remain high and are subject to rampant inflation. Meer
Exploration and Innovation in Design is one of the first books to present both conceptual and computational models of processes which have the potential to produce innovative results at early stages of design. Meer
Time-frequency analysis is a modern branch of harmonic analysis. It com prises all those parts of mathematics and its applications that use the struc ture of translations and modulations (or time-frequency shifts) for the anal ysis of functions and operators. Meer
Multi-Criteria Decision Making (MCDM) has been one of the fastest growing problem areas in many disciplines. The central problem is how to evaluate a set of alternatives in terms of a number of criteria. Meer
A compact guide to knowledge management, this book makes the subject accessible without oversimplifying it. Organizational issues like strategy and culture are discussed in the context of typical knowledge management processes. Meer
Multifractal Based Network Traffic Modeling provides an overview of existing broadband traffic modeling based on the Poisson process and its variants like the MM1 models. Meer
In Decision Modelling And Information Systems: The Information Value Chain the authors explain the interrelationships between the decision support, decision modelling, and information systems. Meer
A logic view of 0-1 integer programming problems, providing new insights into the structure of problems that can lead the researcher to more effective solution techniques depending on the problem class. Meer
Meta-heuristics have developed dramatically since their inception in the early 1980s. They have had widespread success in attacking a variety of practical and difficult combinatorial optimization problems. Meer
Fuzzy Logic Foundations and Industrial Applications is an organized edited collection of contributed chapters covering basic fuzzy logic theory, fuzzy linear programming, and applications. Meer
TEX has always been regarded as the most elegant and powerful system for computer typesetting. However, its widespread use beyond academia was hampered by its complexity. Meer
"Decision Systems and Non-stochastic Randomness" is the first systematic presentation and mathematical formalization (including existence theorems) of the statistical regularities of non-stochastic randomness. Meer
Parallel Scientific Computing and Optimization introduces new developments in the construction, analysis, and implementation of parallel computing algorithms. Meer
This book presents a unified theory of rare event simulation and the variance reduction technique known as importance sampling from the point of view of the probabilistic theory of large deviations. Meer
This text takes readers in a clear and progressive format from simple to recent and advanced topics in pure and applied probability such as contraction and annealed properties of non-linear semi-groups, functional entropy inequalities, empirical process convergence, increasing propagations of chaos, central limit, and Berry Esseen type theorems as well as large deviation principles for strong topologies on path-distribution spaces. Meer
This book is a comprehensive and accessible introduction to the cross-entropy (CE) method. The CE method started life around 1997 when the first author proposed an adaptive algorithm for rare-event simulation using a cross-entropy minimization technique. Meer
Postponement strategy is one of the major supply chain management (SCM) pr- tices that has a discernible impact on rms’ competitive advantage and organi- tional performance. Meer
This volume reflects the theme of the INFORMS 2004 Meeting in Denver: Back to OR Roots. Emerging as a quantitative approach to problem-solving in World War II, our founders were physicists, mathematicians, and engineers who quickly found peace-time uses. Meer
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